NCBI Accession #
NP_171908.1
NCBI GenBank Nucleotide #
NM_100293.3
NCBI Official Full Name
multidrug resistance-associated protein 5
NCBI Official Symbol
ABCC5
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA ATP BINDING CASSETTE TRANSPORTER C5; Arabidopsis thaliana ATP-binding cassette C5; ATABCC5; ATMRP5; ATP BINDING CASSETTE TRANSPORTER C5; ATP-binding cassette C5; MULTIDRUG RESISTANCE PROTEIN 5; multidrug resistance-associated protein
NCBI Protein Information
multidrug resistance-associated protein 5
NCBI Summary
encodes a high-affinity inositol hexakisphosphate transporter that plays a role in guard cell signaling and phytate storage. It is a member of MRP subfamily / ABC transporter subfamily C.
UniProt Synonym Gene Names
MRP5; ABC transporter ABCC.5; AtABCC5
UniProt Protein Name
ABC transporter C family member 5
UniProt Synonym Protein Names
ATP-energized glutathione S-conjugate pump 5; Glutathione S-conjugate-transporting ATPase 5; Multidrug resistance-associated protein 5
UniProt Primary Accession #
Q7GB25
UniProt Secondary Accession #
O65619; Q56ZX0
UniProt Related Accession #
Q7GB25
UniProt Comments
Pump for glutathione S-conjugates. Involved in regulation of K+ and Na+ cell content. Mediates resistance to NaCl and Li+, confers sensitivity to sulfonylurea drugs such as glibenclamide (inducer of stomatal opening), and required for stomatal opening regulation by auxin, abscisic acid (ABA) and external Ca2+. Transports oestradiol-17-(beta-D-glucuronide) (E217G). Involved in the root auxin content regulation that controls the transition from primary root elongation to lateral root formation. Plays a role in ABA-mediated germination inhibition (PubMed:11296221, PubMed:11855639, PubMed:12943546, PubMed:14684837). High-affinity inositol hexakisphosphate transporter that plays a role in guard cell signaling and phytic acid storage. Required for phytic acid accumulation in developing seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds (PubMed:19797057).