NCBI Accession #
NP_001189675.1
NCBI GenBank Nucleotide #
NM_001202746.1
NCBI Official Full Name
multidrug resistance-associated protein 2
NCBI Official Symbol
ABCC2
NCBI Official Synonym Symbols
ABC TRANSPORTER; Arabidopsis thaliana ATP-binding cassette C2; AtABCC2; ATMRP2; ATP-binding cassette C2; EST4; MRP2; multidrug resistance-associated protein 2; T29F13.13; T29F13_13
NCBI Protein Information
multidrug resistance-associated protein 2
NCBI Summary
encodes a multidrug resistance-associated protein that is MgATP-energized glutathione S-conjugate pump. An ABCC-type arsenite-phytochelatin transporter. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.
UniProt Synonym Gene Names
EST4; MRP2; ABC transporter ABCC.2; AtABCC2
UniProt Protein Name
ABC transporter C family member 2
UniProt Synonym Protein Names
ATP-energized glutathione S-conjugate pump 2; Glutathione S-conjugate-transporting ATPase 2; Multidrug resistance-associated protein 2
UniProt Primary Accession #
Q42093
UniProt Secondary Accession #
O22449; O24526; O48907; O48908; O64590
UniProt Related Accession #
Q42093
UniProt Comments
Pump for glutathione S-conjugates. Mediates the transport of S-conjugates such as GSH, S-(2,4-dinitrophenyl)-glutathione (DNP-GS), GSSG, cyanidin 3-glucoside-GS (C3G-GS) and metolachlor-GS (MOC-GS), glucuronides such as 17-beta-estradiol 17-(beta-D-glucuronide) (E217betaG), and of the chlorophyll catabolite such as B.napus nonfluorescent chlorophyll catabolite (Bn-NCC-1).