ABC transporter B family member 4 (ABCB4), Recombinant Protein
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ABC transporter B family member 4 (ABCB4), Recombinant Protein

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Cat: RP03959
Size: 1 mg (E-Coli)/ 1 mg (Yeast)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana ABC transporter B family member 4 (ABCB4) , partial
Product Gene Name
ABCB4 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
139,028 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
ABC transporter B family

NCBI/Uniprot Data

NCBI Accession #
NP_001323911.1
NCBI GI #
1063707072
NCBI GenBank Nucleotide #
NM_001337237.1
NCBI GeneID
819314
NCBI Official Full Name
ATP binding cassette subfamily B4
NCBI Official Symbol
ABCB4
NCBI Official Synonym Symbols
ARABIDOPSIS P-GLYCOPROTEIN 4; AtABCB4; ATP binding cassette subfamily B4; ATP-binding cassette B4; ATPGP4; F14M4.17; MDR4; MULTIDRUG RESISTANCE 4; P-GLYCOPROTEIN 4; PGP4
NCBI Protein Information
ATP binding cassette subfamily B4
NCBI Summary
Encodes an auxin efflux transmembrane transporter that is a member of the multidrug resistance P-glycoprotein (MDR/PGP) subfamily of ABC transporters. Functions in the basipetal redirection of auxin from the root tip. Exhibits apolar plasma membrane localization in the root cap and polar localization in tissues above and is involved in root hair elongation.
UniProt Gene Name
ABCB4
UniProt Synonym Gene Names
MDR4; PGP4; ABC transporter ABCB.4; AtABCB4
UniProt Protein Name
ABC transporter B family member 4
UniProt Synonym Protein Names
Multidrug resistance protein 4; P-glycoprotein 4
UniProt Primary Accession #
O80725
UniProt Related Accession #
O80725
UniProt Comments
Auxin influx transporter that mediates the transport of auxin in roots. Contributes to the basipetal transport in hypocotyls and root tips by establishing an auxin uptake sink in the root cap. Confers sensitivity to 1-N-naphthylphthalamic acid (NPA). Regulates the root elongation, the initiation of lateral roots and the development of root hairs. Can transport IAA, indole-3-propionic acid, NPA syringic acid, vanillic acid and some auxin metabolites, but not 2,4-D and 1-naphthaleneacetic acid.

For research use only, not for clinical use.