NCBI Accession #
NP_200635.1
NCBI GenBank Nucleotide #
NM_125212.3
NCBI Official Full Name
ABC transporter of the mitochondrion 3
NCBI Official Symbol
ABCB25
NCBI Official Synonym Symbols
ABC transporter of the mitochondrion 3; ARABIDOPSIS THALIANA ABC TRANSPORTER OF THE MITOCHONDRION 3; ATATM3; ATM3; ATP-binding cassette B25; HALF-MOLECULE ABC TRANSPORTER ATM3; MCK7.14; MCK7_14; STA1; STARIK 1
NCBI Protein Information
ABC transporter of the mitochondrion 3
NCBI Summary
Encodes a mitochondrial half-molecule ABC transporter, a member of ATM subfamily. Mutants are dwarfed, chlorotic plants with altered leaf morphology. ATM3 transcription is induced by Cd(II) or Pb(II). Involved in heavy metal resistance. Arabidopsis thaliana has three ATM genes, namely ATM1, ATM2 and ATM3. Only ATM3 has an important function for plant growth. Role in Moco biosynthesis.
UniProt Synonym Gene Names
ATM3; STA1; ABC transporter ABCB.25; AtABCB25; AtATM3; Iron-sulfur clusters transporter ATM3
UniProt Protein Name
ABC transporter B family member 25, mitochondrial
UniProt Synonym Protein Names
ABC transporter of the mitochondrion 3; AtATM3; Iron-sulfur clusters transporter ATM3; Protein STARIK 1
UniProt Primary Accession #
Q9LVM1
UniProt Secondary Accession #
Q9LF78
UniProt Related Accession #
Q9LVM1
UniProt Comments
Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not required for mitochondrial and plastid Fe-S enzymes. Probably involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol. Mediates glutathione-dependent resistance to heavy metals such as cadmium and lead, as well as their transport from roots to leaves. Regulates nonprotein thiols (NPSH) and the cellular level of glutathione (GSH).