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65-kDa microtubule-associated protein 1 (MAP65-1), Recombinant Protein
Cat: RP08350
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana 65-kDa microtubule-associated protein 1 (MAP65-1) , partial
Product Gene Name
MAP65-1 recombinant protein
Product Synonym Gene Name
MAP65-1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
65,785 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
65-kDa microtubule-associated protein
NCBI/Uniprot Data
NCBI Accession #
NP_001332196.1
NCBI GI #
1063741355
NCBI GenBank Nucleotide #
NM_001345120.1
NCBI GeneID
835616
NCBI Official Full Name
microtubule-associated proteins 65-1
NCBI Official Symbol
MAP65-1
NCBI Official Synonym Symbols
ATMAP65-1; MCO15.18; MCO15_18; microtubule-associated proteins 65-1
NCBI Protein Information
microtubule-associated proteins 65-1
NCBI Summary
Binds and bundles microtubules. Plays a role in stabilizing anti-parallel microtubules in the central spindle at anaphase to early cytokinesis but is not essential at the midline of the phragmoplast at later stages. The timing with which the MAP65-1 was targeted to the spindle appears to be regulated by a phosphorylation sensitive switch. Enhances microtubule polymerization, promotes nucleation and stabilizes microtubules against cold treatment and dilution.
UniProt Gene Name
MAP65-1
UniProt Synonym Gene Names
AtMAP65-1
UniProt Protein Name
65-kDa microtubule-associated protein 1
UniProt Primary Accession #
Q9FLP0
UniProt Related Accession #
Q9FLP0
UniProt Comments
Microtubule-associated protein that bundle and stabilize adjacent microtubules (MT) of the cell cortex. Enhances MT nucleation. Can also bind to tubulin dimers and promotes their polymerization. Confers MT resistance to the drug propyzamide and cold conditions. Plays a role in the central spindle at anaphase to early cytokinesis but is not essential at the midline of the phragmoplast at later stages. Represses metaphase spindle organization and the transition to anaphase in dephosphorylated active form. Promotes the formation of a planar network of antiparallel microtubules. May be involved in stomatal movement modulation by regulating the dynamic and arrangement of cortical MT.
For research use only, not for clinical use.