NCBI Accession #
NP_198599.1
NCBI GenBank Nucleotide #
NM_123142.5
NCBI Official Full Name
oxoprolinase 1
NCBI Official Symbol
OXP1
NCBI Official Synonym Symbols
K22F20.70; K22F20_70; oxoprolinase 1
NCBI Protein Information
oxoprolinase 1
NCBI Summary
Encodes a 5-oxoprolinase that acts in the glutathione degradation pathway and in 5-oxoproline metabolism.
UniProt Synonym Gene Names
5-OPase
UniProt Protein Name
5-oxoprolinase
UniProt Synonym Protein Names
5-oxo-L-prolinase; 5-OPase; Protein OXOPROLINASE 1; Pyroglutamase
UniProt Primary Accession #
Q9FIZ7
UniProt Secondary Accession #
Q0WQ06
UniProt Related Accession #
Q9FIZ7
UniProt Comments
Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway.