NCBI Accession #
NP_171918.1
NCBI GenBank Nucleotide #
NM_100303.4
NCBI Official Full Name
3-ketoacyl-CoA synthase 2
NCBI Official Symbol
KCS2
NCBI Official Synonym Symbols
3-ketoacyl-CoA synthase 2; F20D22.1; F20D22_1
NCBI Protein Information
3-ketoacyl-CoA synthase 2
NCBI Summary
Encodes KCS2, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
UniProt Synonym Gene Names
VLCFA condensing enzyme 2
UniProt Protein Name
3-ketoacyl-CoA synthase 2
UniProt Synonym Protein Names
Docosanoic acid synthase
UniProt Primary Accession #
Q5XEP9
UniProt Secondary Accession #
O64485; Q56WE1; Q8VXW2
UniProt Related Accession #
Q5XEP9
UniProt Comments
Mediates the synthesis of VLCFAs from 22 to 26 carbons in length (e.g. C22, C24, C26) (PubMed:15277688). Involved in the elongation of C20 fatty acid suberin precursors (PubMed:18786002). Functionally redundant with KCS20 in the two-carbon elongation of C22 fatty acids that is required for cuticular wax and root suberin biosynthesis (PubMed:19619160).