NCBI Accession #
NP_196924.1
NCBI GenBank Nucleotide #
NM_121424.6
NCBI Official Full Name
isopropylmalate dehydrogenase 1
NCBI Official Symbol
IMD1
NCBI Official Synonym Symbols
ARABIDOPSIS ISOPROPYLMALATE DEHYDROGENASE 1; ATIMD1; isopropylmalate dehydrogenase 1; MUA22.20; MUA22_20
NCBI Protein Information
isopropylmalate dehydrogenase 1
NCBI Summary
The AtIMD1 is one out of 3 genes encoding the enzyme 3-isopropylmalate dehydrogenase involved in leucine biosynthesis in Arabidopsis. Its subcellular location has been targeted to plastids. Encodes methylthioalkylmalate dehydrogenase. Involved in glucosinolate biosynthesis, in methionine chain elongation.
UniProt Synonym Gene Names
3-IPM-DH 3; IMDH 3
UniProt Protein Name
3-isopropylmalate dehydrogenase 3, chloroplastic
UniProt Synonym Protein Names
Beta-IPM dehydrogenase 3
UniProt Primary Accession #
Q9FMT1
UniProt Secondary Accession #
Q8VXU4
UniProt Related Accession #
Q9FMT1
UniProt Comments
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.