NCBI Accession #
NP_194633.1
NCBI GenBank Nucleotide #
NM_119048.4
NCBI Official Full Name
regulatory particle AAA-ATPase 2A
NCBI Official Symbol
RPT2a
NCBI Official Synonym Symbols
26S PROTEASOME AAA-ATPASE SUBUNIT RPT2A; F19B15.70; F19B15_70; regulatory particle AAA-ATPase 2A
NCBI Protein Information
regulatory particle AAA-ATPase 2A
NCBI Summary
RPT2a encodes the 26S proteasome subunit. It is required for root meristem maintenance, and regulates gametogenesis. RPT2a is also shown to regulate gene silencing via DNA methylation.
UniProt Synonym Gene Names
HLR
UniProt Protein Name
26S proteasome regulatory subunit 4 homolog A
UniProt Synonym Protein Names
26S proteasome AAA-ATPase subunit RPT2a; 26S proteasome subunit 4 homolog A; Protein HALTED ROOT; Regulatory particle triple-A ATPase subunit 2a
UniProt Primary Accession #
Q9SZD4
UniProt Secondary Accession #
Q9SEI5
UniProt Related Accession #
Q9SZD4
UniProt Comments
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Is required for the maintenance of postembryonic root and shoot meristems. Has a specific role in the regulation of organs size.