26S proteasome non-ATPase regulatory subunit 4 (MBP1), Recombinant Protein
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26S proteasome non-ATPase regulatory subunit 4 (MBP1), Recombinant Protein

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Cat: RP00924
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana 26S proteasome non-ATPase regulatory subunit 4 (MBP1)
Product Gene Name
MBP1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MVLEATMICI DNSEWMRNGD YSPSRLQAQT EAVNLLCGAK TQSNPENTVG ILTMAGKGVR VLTTPTSDLG KILACMHGLD VGGEINLTAA IQIAQLALKH RQNKNQRQRI IVFAGSPIKY EKKALEIVGK RLKKNSVSLD IVNFGEDDDE EKPQKLEALL TAVNNNDGSH IVHVPSGANA LSDVLLSTPV FTGDEGASGY VSAAAAAAAA GGDFDFGVDP NIDPELALAL RVSMEEERAR QEAAAKKAAD EAGQKDKDGD TASASQETVA RTTDKNAEPM DEDSALLDQA IAMSVGDVNM SEAADEDQDL ALALQMSMSG EESSEATGAG NNLLGNQAFI SSVLSSLPGV DPNDPAVKEL LASLPDESKR TEEEESSSKK GEDEKK
Sequence Positions
1-386, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
40,757 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Transcription factor

NCBI/Uniprot Data

NCBI Accession #
NP_195575.1
NCBI GI #
15233973
NCBI GenBank Nucleotide #
NM_120024.3
NCBI GeneID
830019
NCBI Official Full Name
regulatory particle non-ATPase 10
NCBI Official Symbol
RPN10
NCBI Official Synonym Symbols
ATMCB1; MBP1; MCB1; MULTIUBIQUITIN CHAIN BINDING PROTEIN; MULTIUBIQUITIN CHAIN BINDING PROTEIN 1; MULTIUBIQUITIN-CHAIN-BINDING PROTEIN 1; regulatory particle non-ATPase 10; T9A14.7
NCBI Protein Information
regulatory particle non-ATPase 10
NCBI Summary
Regulatory particle non-ATPase subunit of the 26S proteasome with multiubiquitin-chain-binding capabilities
UniProt Gene Name
RPN10
UniProt Synonym Gene Names
MBP1; MCB1; AtRPN10; AtMCB1
UniProt Protein Name
26S proteasome non-ATPase regulatory subunit 4 homolog
UniProt Synonym Protein Names
26S proteasome regulatory subunit RPN10; AtRPN10; 26S proteasome regulatory subunit S5A homolog; Multiubiquitin chain-binding protein 1; AtMCB1
UniProt Primary Accession #
P55034
UniProt Secondary Accession #
Q8L9G3
UniProt Related Accession #
P55034
UniProt Comments
Plays a role in maintaining the structural integrity of the 19S regulatory particle (RP), subcomplex of the 26S proteasome. Plays a major role in both the direct and indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a potential docking subunit for both ubiquitin receptors RAD23s and DSK2s. Plays a role in the growth and development via the proteasome-dependent degradation of the ABA-signaling protein ABI5/DPBF1. Plays an important role for balancing cell expansion with cell proliferation rates during shoot development.

For research use only, not for clinical use.