26S protease regulatory subunit 6A homolog B (RPT5B), Recombinant Protein
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26S protease regulatory subunit 6A homolog B (RPT5B), Recombinant Protein

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Cat: RP03962
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana 26S protease regulatory subunit 6A homolog B (RPT5B)
Product Gene Name
RPT5B recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MATAMAEDTS FEGDQLASMT TDDIGRASRL LANEIRILKE ESQRTNLDLE SVKEKIKENQ EKIKLNKQLP YLVGNIVEIL EMSPEDDAEE DGANIDLDSQ RKGKCVVLKT STRQTIFLPV VGLVDPDTLK PGDLVGVNKD SYLILDTLPS EYDSRVKAME VDEKPTEDYN DIGGLEKQIQ ELVEAIVLPM THKEQFEKLG IRPPKGVLLY GPPGTGKTLM ARACAAQTNA TFLKLAGPQL VQMFIGDGAK LVRDAFLLAK EKSPCIIFID EIDAIGTKRF DSEVSGDREV QRTMLELLNQ LDGFSSDDRI KVIAATNRAD ILDPALMRSG RLDRKIEFPH PTEEARGRIL QIHSRKMNVN ADVNFEELAR STDDFNGAQL KAVCVEAGML ALRRDATEVN HEDFNEGIIQ VQAKKKASLN YYA
Sequence Positions
1-423, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
47,038 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
26S protease regulatory

NCBI/Uniprot Data

NCBI Accession #
NP_172384.1
NCBI GI #
15217431
NCBI GenBank Nucleotide #
NM_100781.5
NCBI GeneID
837431
NCBI Official Full Name
26S proteasome AAA-ATPase subunit RPT5B
NCBI Official Symbol
RPT5B
NCBI Official Synonym Symbols
26S proteasome AAA-ATPase subunit RPT5B; F7G19.2; F7G19_2
NCBI Protein Information
26S proteasome AAA-ATPase subunit RPT5B
NCBI Summary
Encodes RPT5b (Regulatory Particle 5b), one of the six AAA-ATPases of the proteasome regulatory particle. Essential for gametophyte development. In Arabidopsis, the RPT5 subunit is encoded by two highly homologous genes, RPT5a and RPT5b. RPT5a and RPT5b show accession-dependent functional redundancy. In Wassilewskija (Ws) accession: mutant alleles of RPT5a displayed 50% pollen lethality, indicating that RPT5a is essential for male gametophyte development. In the Columbia (Col) accession, a rpt5a mutant allele did not display such a phenotype because the RPT5b Col allele complements the rpt5a defect in the male gametophyte, whereas the RPT5b Ws allele does not. Double rpt5a rpt5b mutants in Col background showed a complete male and female gametophyte lethal phenotype.
UniProt Gene Name
RPT5B
UniProt Synonym Gene Names
TBP1; TBP-1 homolog B
UniProt Protein Name
26S proteasome regulatory subunit 6A homolog B
UniProt Synonym Protein Names
26S proteasome AAA-ATPase subunit RPT5b; Proteasome 26S subunit 6A homolog B; Regulatory particle triple-A ATPase subunit 5b; Tat-binding protein 1 homolog B; TBP-1 homolog B
UniProt Primary Accession #
O04019
UniProt Secondary Accession #
Q93V77
UniProt Related Accession #
O04019
UniProt Comments
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.

For research use only, not for clinical use.