26S protease regulatory subunit 6A homolog A (RPT5A), Recombinant Protein
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26S protease regulatory subunit 6A homolog A (RPT5A), Recombinant Protein

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Cat: RP03982
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana 26S protease regulatory subunit 6A homolog A (RPT5A)
Product Gene Name
RPT5A recombinant protein
Product Synonym Gene Name
RPT5A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
ATPMVEDTSS FEEDQLASMS TEDITRATRL LDNEIRILKE DAQRTNLECD SYKEKIKENQ EKIKLNKQLP YLVGNIVEIL EMNPEDDAEE DGANIDLDSQ RKGKCVVLKT STRQTIFLPV VGLVDPDSLK PGDLVGVNKD SYLILDTLPS EYDSRVKAME VDEKPTEDYN DIGGLEKQIQ ELVEAIVLPM THKERFEKLG VRPPKGVLLY GPPGTGKTLM ARACAAQTNA TFLKLAGPQL VQMFIGDGAK LVRDAFQLAK EKAPCIIFID EIDAIGTKRF DSEVSGDREV QRTMLELLNQ LDGFSSDERI KVIAATNRAD ILDPALMRSG RLDRKIEFPH PTEEARARIL QIHSRKMNVH PDVNFEELAR STDDFNGAQL KAVCVEAGML ALRRDATEVN HEDFNEGIIQ VQAKKKASLN YYA
Sequence Positions
2-424, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
47,480 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
26S protease regulatory

NCBI/Uniprot Data

NCBI Accession #
NP_187204.1
NCBI GI #
15230005
NCBI GenBank Nucleotide #
NM_111426.4
NCBI GeneID
819718
NCBI Official Full Name
regulatory particle triple-A ATPase 5A
NCBI Official Symbol
RPT5A
NCBI Official Synonym Symbols
19S PROTEASOME REGULATORY COMPLEX SUBUNIT S6A; 26S PROTEASOME AAA-ATPASE SUBUNIT; ATS6A.2; F22F7.1; F22F7_1; regulatory particle triple-A ATPase 5A
NCBI Protein Information
regulatory particle triple-A ATPase 5A
NCBI Summary
Encodes RPT5a (Regulatory Particle 5a), one of the six AAA-ATPases of the proteasome regulatory particle. Essential for gametophyte development. In Arabidopsis, the RPT5 subunit is encoded by two highly homologous genes, RPT5a and RPT5b. RPT5a and RPT5b show accession-dependent functional redundancy. In Wassilewskija (Ws) accession: mutant alleles of RPT5a displayed 50% pollen lethality, indicating that RPT5a is essential for male gametophyte development. In the Columbia (Col) accession, a rpt5a mutant allele did not display such a phenotype because the RPT5b Col allele complements the rpt5a defect in the male gametophyte, whereas the RPT5b Ws allele does not. Double rpt5a rpt5b mutants in Col background showed a complete male and female gametophyte lethal phenotype.
UniProt Gene Name
RPT5A
UniProt Synonym Gene Names
ATS6A.2; TBP1; TBP-1 homolog A
UniProt Protein Name
26S proteasome regulatory subunit 6A homolog A
UniProt Synonym Protein Names
26S proteasome AAA-ATPase subunit RPT5a; Proteasome 26S subunit 6A homolog A; Regulatory particle triple-A ATPase subunit 5a; Tat-binding protein 1 homolog A; TBP-1 homolog A
UniProt Primary Accession #
Q9SEI2
UniProt Secondary Accession #
Q8H195; Q9SWY7
UniProt Related Accession #
Q9SEI2
UniProt Comments
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Plays a essential role in the gametophyte development.

For research use only, not for clinical use.