NCBI Accession #
NP_173285.2
NCBI GenBank Nucleotide #
NM_101708.3
NCBI Official Full Name
methylthioalkylmalate synthase-like 4
NCBI Official Symbol
MAML-4
NCBI Official Synonym Symbols
F15H18.3; F15H18_3; IPMS1; ISOPROPYLMALATE SYNTHASE 1; methylthioalkylmalate synthase-like 4
NCBI Protein Information
methylthioalkylmalate synthase-like 4
NCBI Summary
Encodes an active Arabidopsis isopropylmalate synthase IPMS1. Involved in leucine biosynthesis. Do not participate in the chain elongation of glucosinolates. Expressed constitutively throughout the plant. Loss of IPMS1 can be compensated by a second isopropylmalate synthase gene IPMS2 (At1g74040).
UniProt Synonym Gene Names
MAML-4
UniProt Protein Name
2-isopropylmalate synthase 1, chloroplastic
UniProt Synonym Protein Names
Methylthioalkylmalate synthase-like 4
UniProt Primary Accession #
Q9LPR4
UniProt Related Accession #
Q9LPR4
UniProt Comments
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Involved in Leu biosynthesis, but do not participate in the chain elongation of glucosinolates.