NCBI Accession #
NP_001077884.1
NCBI GenBank Nucleotide #
NM_001084415.2
NCBI Official Full Name
oxophytodienoate-reductase 3
NCBI Official Symbol
OPR3
NCBI Official Synonym Symbols
11-REDUCTASE; 12-OXO-PHYTODIENOATE REDUCTASE; 12-OXOPHYTODIENOATE-10; AtOPR3; DDE1; DELAYED DEHISCENCE 1; F5K7.19; F5K7_19; oxophytodienoate-reductase 3
NCBI Protein Information
oxophytodienoate-reductase 3
NCBI Summary
Encodes a 12-oxophytodienoate reductase that is required for jasmonate biosynthesis. Mutants are male sterile and defective in pollen dehiscence. Shows activity towards 2,4,6-trinitrotoluene.
UniProt Synonym Gene Names
DDE1; AtOPR3; OPDA-reductase 3
UniProt Protein Name
12-oxophytodienoate reductase 3
UniProt Synonym Protein Names
12-oxophytodienoate-10,11-reductase 3; AtOPR3; OPDA-reductase 3
UniProt Primary Accession #
Q9FUP0
UniProt Secondary Accession #
Q9LLD6; Q9SCY4; Q9XHD2; Q9ZQ01; B9DGR2
UniProt Related Accession #
Q9FUP0
UniProt Comments
Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. Required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program. In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively. Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT).