Phenotype Analysis - CD BioSciences

service-banner

Phenotype Analysis

Phenotype Analysis

Analyzing phenotypes of cells is required for understanding gene and protein functions, as well as dissecting the mechanisms controlling those phenotypes in basic life science research. It is also a vital part of drug discovery and development in biomedical research.  

Cellular signaling pathways regulate cellular processes such as cell proliferation, apoptosis, inflammation, autophagy and antioxidant defenses. Thus, it is of great interest to understand how changes in cell signaling affect the downstream phenotypes.

CD BioSciences offers a complete portfolio of high-quality assay services based on cultured cells to assess the biochemistry and physiology of both healthy and diseased cells. These assays, analyzing cell proliferation, toxicity, viability, apoptosis, migration, oxidative stress condition, allow researchers to capture the status of cellular activity and uncover relevant mechanisms.

Gene sequence

Our Services

Cell-based assays allow phenotypic profiling of cells or tissues of interest under genetic modifications or therapeutic treatments. These assays have the potential to generate useful data leading to advanced scientific discoveries.

Cell Health Assays
Cell health assays determine if a gene or a treatment is necessary for normal cellular functions such as proliferation, viability or cell death. These assays include but not limited to:

Phenotype-Analysis

  • Viability Assays
  • Cytotoxicity Assays
  • Apoptosis and Necrosis Assays
  • Oxidative Stress Assays
  • Inflammation Assays
  • Autophagy Detection Assays
  • Proliferation Assays

Motility Assays

Cellular motility is the spontaneous movement of a cell from one location to another by consumption of energy. Cells exhibit a wide range of movement, including the migration of cells along a surface or through tissue. The motility of cells is vital in many biological processes including embryological development, wound healing, and tumor progression. Cell motility assays determine how physical, chemical, and genetic manipulations affect the migratory behavior of cells.

Cell Migration Assays
Cell Invasion Assays
  • Colorimetric Cell Invasion Assays
  • Fluorometric Cell Invasion Assays
Cell Adhesion Assays
  • Anoikis Assay
  • Colorimetric Cell Adhesion Assays
  • Fluorometric Cell Adhesion Assays
  • Leukocyte Adhesion Assays
  • Tumor Adhesion Assays

Angiogenesis Assays

Angiogenesis is a physiological process through which new blood vessels form from pre-existing vessels during wound healing and normal development. It is a highly regulated process coordinating tightly with cell proliferation, differentiation, migration and communication.

Angiogenesis assays are crucial for understanding the involvement of angiogenesis in physiological and pathological conditions such as embryonic growth, would healing and tumor development.

In Vitro In Vivo
  • Endothelial Cell Tube Formation Assay
  • Matrix Invasion Assay
  • Transwell Migration Assay
  • Thymidine Incorporation Assay
  • Rat Aortic Ring Assay
  • Corneal Angiogenesis Assay
  • Matrigel Plug Assay
  • Hindlimb Ischemia Assay
  • Chick Chorioallantoic Membrane (CAM) Assay

Features

CD BioSciences offers cost-effect, high quality and hassle-free cell phenotype assay services to our clients worldwide. We guarantee to deliver our results on time. Please feel free to contact us.

For research use only. Not intended for any clinical use.