Caspase-8 (Pro) Antibody - CD BioSciences


Caspase-8 (Pro) Antibody

Caspase-8 (Pro) Antibody


Size Price
100 µL Online Inquiry
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Target Information
Target Name Caspase-8
Gene Abbr. CASP8
Gene ID 841
Full Name caspase 8
Alias ALPS2B, CAP4, Casp-8, FLICE, MACH
Introduction Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage.
Product Details
Host Rabbit
Clonality Monoclonal
Clone No. SD08-06
Isotype IgG
Immunogen Recombinant Protein.
Application WB, IF, IHC
Dilutions Western Blot (1:1000-1:2000); Immunofluorescence (1:50-1:200); Immunohistochemistry (1:50-1:200)
MW(KDa) 18, 43, 57
Reactivity Human
Storage & Handling
Storage Buffer TBS (pH 7.4), 1% BSA, 40% Glycerol.
Preservative 0.05% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.