Breeding & Genotyping - CD BioSciences

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Breeding & Genotyping

Breeding & Genotyping

Model organisms, such as mice, are widely used in biological research labs around the world. Breeding and genotyping are inevitable in a well preformed study using model organisms. It is important to carefully decide the number, genotype, sex/gender of animals needed in your research. It is also necessary to obtain information about the stain background and breading history when animals are acquired from others.

To maintain a defined genetic background (inbred, outbred, or hybrid) and to minimize animal-to-animal variations in phenotype, animals should be accurately bred and genotyped. CD BioSciences offers a series of low-cost, speed breeding and genotyping services to provide you with abundant research models. With a complete portfolio of research services, we produce genetically well-defined congenic animals of high health status to meet all your needs.

Breeding and genotyping

Our Breeding Workflow

Workflow of breeding at CD BioSciences

We offer breeding services for all stains of animal models, including but not limited to mice, rats, rabbits, gerbils, hamsters, guinea pigs, ferrets and simian species.

Our Genotyping Services

  • Traditional Distal Tissue Biopsy, and PCR

    Determining the genotype of animal models to identify knockouts, knockins, and transgenes.

  • Copy Number Variation Analysis

    Determining the approximate copy number of a transgene present in an animal to potentially monitor gene expression.

  • Transgene Zygosity Analysis

    Distinguishing heterozygous from homozygous transgenic animals without knowing the location of the transgene.

  • Transgene Mapping Analysis

    Precisely identifying the exact integration sites of a transgene and determining structural changes in the transgene and genomic regions surrounding the transgene.

  • Genome-wide SNP Scanning

    Analyzing SNPs (single nucleotide polymorphisms) in the genome to confirm strain identity, and monitor genetic quality.

  • Sequencing-based Genotyping

    Whole genome sequencing to verify genetically modified animals and characterize mutant lines.

  • Genome Wide Association Studies (GWAS)

    Determining the association of specific genetic variation in different individuals with a particular trait/phenotype/disease.

  • Gene Expression Profiling

    Determining whether and in which tissues a gene is expressed and quantifying the level of gene expression.

Features

CD BioSciences offers cost-effect, high quality and hassle-free breeding and genotyping services to our clients worldwide. We guarantee to deliver our products and results on time. Please feel free to contact us.

For research use only. Not intended for any clinical use.